PUBLICATIONS
PEER-REVIEWED ARTICLES AND REVIEWS
1. Zhang, L. M., "X-ray absorption spectroscopy of metalloproteins" in “Methods in Molecular Biology – Complex Metalloproteins” (invited book chapter) (Accepted)
2. Jiang, J+. Beltran, D.G+, Schacht, A., Zhang, L*, and Du, L*. “Functional and structural analysis of phenazine O-methyltransferase LaPhzM from Lysobacter antibioticus OH13 and one-pot enzymatic synthesis of the antibiotic myxin.” (2018) ACS Chem. Biol. (Accepted)
(+these authors contribute equally, *corresponding authors)
3. Li, S., Wu, X., Zhang, L., Shen, Y. and Du, L. “Activation of a cryptic gene cluster in Lysobacter enzymogenes reveals a module/domain portable mechanism of nonribosomal peptide synthetases in the biosynthesis of pyrrolopyrazines.” (2017) Org. Lett. 19: 5010-5013.
4. Spatzal, T., Schlesier, J., Burger, E. M., Sippel, D., Zhang, L., Andrade, S. L. A., Rees, D. C., Einsle, O. “Nitrogenase FeMoco investigated by spatially resolved anomalous dispersion refinement.” (2016) Nat. Commun.. 7: 10902-10532.
5. Anderson, J., Cutsail III, G.E., Rittle, J., Connor, B. A., Gunderson, W. A., Zhang, L.*, Hoffman, B. M.* and Peters, J. C.* “Characterization of an Fe≡N-NH2 intermediate relevant to catalytic N2 reduction to NH3.” (2015) J Am. Chem. Soc. 137: 7803-7809.
(*corresponding authors)
6. Mattle, D., Zhang, L., Gourdon, P., Nissen, P., Rees, D. C. and Meloni, G. “A sulfur-based transport pathway for Cu+-ATPases.” (2015) EMBO J. 16: 728-740.
7. Morrison, C., Hoy, J., Zhang, L., Einsle, O. and Rees, D. C. “Substrate pathways in the nitrogenase MoFe protein by experimental identification of small molecule binding sites.” (2015) Biochemistry 54: 2052-2060.
8. Zhang, L., Morrison, C., Kaiser, J. T. and Rees, D. C. “Nitrogenae MoFe-protein from Clostridium pasteurianum at 1.08 Å Resolution: Comparison to the Azotobacterer vinelandii MoFe-protein.” (2015) Acta Cryst D 71: 274-282.
9. Meloni, G.+*, Zhang, L.+* and Rees, D. C.* “Transmembrane Type-2-like Cu2+ site in the P1B-3-type ATPase CopB: implications for metal selectivity.” (2014) ACS Chem. Biol. 9(1): 116-121.
(+these authors contribute equally, *corresponding authors)
10. Zhang, L., Kaiser, J. T., Meloni, G., Yang, K. Y., Spatzal, T., Andrade, S. L. A., Einsle, O., Howard, J. B. and Rees, D. C. “The sixteenth iron in the nitrogenase MoFe-protein.” (2013) Angew. Chem. Int. Ed. Engl. 52: 10529-10532.
11. Moret, M. E., Zhang, L. and Peters, J. C. “A polar copper-boron one-electron bond.” (2013) J. Am. Chem. Soc. 135: 3792-3795.
12. Pushie, J.M., Zhang, L., Pickering, I. J. and George, G. N. “The fictile coordination chemistry of cuprous-thiolate sites in copper chaperones.” (2012) BBA - Bioenergetics. 1817: 938-947.
13. Spatzal, T., Aksoyoglu, M., Zhang, L. Andrade, S. L.A., Schleicher, E., Weber, S., Rees, D. C. and Einsle, O. “Direct Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor.” (2011) Science. 334:940-940.
14. Ma, Z., Cowart, D. M., Ward, B. P., Arnold, R. J., DiMarchi, R. D., Zhang, L., George, G. N., Scott, R. A. and Giedroc, D. P. “Unnatural amino acid substitution as a Probe of the Allosteric Coupling Pathway in a Mycobacterial Cu(I) Sensor.” (2009) J. Am. Chem. Soc. 131:18044-18045.
15. Zhang, L., Lichtmanneger, J., Summer, K. H., Webb, S., Pickering, I. J. and George, G. N. “Tracing copper-thiomolybdate complexes in a prospective treatment for Wilson’s disease.” (2009) Biochemistry 48:891-897.
16. Bewer, B., Zhang, H., Zhu, Y., Zhang, L., George, G.N., Pickering, I. J. and Chapman, D. “Development of a combined K-edge subtraction and fluorescence subtraction imaging system for small animals.” (2008) Rev. Sci. Instrum. 79:085102-1-085102-3.
17. Zhang, L., Pickering, I. J., Winge, D. R. and George, G. N. “X-ray absorption spectroscopy of cuprous-thiolate clusters in Saccharomyces cerevisiae metallothionein.” (2008) Chem. Biodivers. 5:2042- 2049.
18. Zhang, H., Zhu, Y., Bewer, B., Zhang, L., Korbas, M., Pickering, I. J., George, G. N., Gupta, M. and Chapman, D. “Comparison of iodine K-edge subtraction and fluorescence subtraction imaging in an animal system.” (2008) Nucl. Instrum. Methods Phys. Res. A. 594: 283-291.
19. Chen, X., Hua, H., Balamurugan, K., Kong, X., Zhang, L., George, G. N., Georgiev, O., Schaffner, W. and Giedroc, D. P. “Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.” (2008) Nucleic Acids Res. 36 (9):3128-3138.
20. Zhang, L., Nelson, K. J., Rajagopalan, K.V. and George, G. N. “Structure of molybdenum center in trimethylamine N-oxide reductase from E. Coli.” (2008) Inorg. Chem. 47 (3): 1074-1078.
21. Rigby, K., Zhang, L., Cobine, P. A., Tzagoloff, A., George, G. N. and Winge, D. R. “Characterization of the cytochrome c oxidase assembly factor Cox19 of Saccharomyces cerevisiae.” (2007) J. Biol. Chem. 282 (14): 10233-10244.
22. Coyne, H. J., Ciofi-Baffoni, S., Banci, L., Zhang, L., George, G. N. and Winge, D. R. “The characterization and role of zinc binding in yeast Cox4.” (2007) J. Biol. Chem. 282 (12): 8926- 8934.
23. Liu, T., Ramesh, A., Ward, S. K., Zhang, L., Ma, Z., George, G. N., Talaat, A. M., Sacchettini, J. C. and Giedroc, D. P. “CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator.” (2007) Nature Chem. Biol. 3 (1): 60-68
24. Jiang, D.T., Chen, N., Zhang, L., Malgorzata, K., Wright, G., Igarashi, R., Beauregard, D., Kirkham, M. and McKibben, M. “XAFS at Canadian Light Source.” (2007) AIP Proc. (XAFS13) 882:893-895 (conference paper).
25. Doonan, C. J., Zhang, L., Young, C. G., . “High-resolution X-ray emission spectroscopy of molybdenum compounds.” (2005) Inorg. Chem 44 (8): 2579-2581.
1. Zhang, L. M., "X-ray absorption spectroscopy of metalloproteins" in “Methods in Molecular Biology – Complex Metalloproteins” (invited book chapter) (Accepted)
2. Jiang, J+. Beltran, D.G+, Schacht, A., Zhang, L*, and Du, L*. “Functional and structural analysis of phenazine O-methyltransferase LaPhzM from Lysobacter antibioticus OH13 and one-pot enzymatic synthesis of the antibiotic myxin.” (2018) ACS Chem. Biol. (Accepted)
(+these authors contribute equally, *corresponding authors)
3. Li, S., Wu, X., Zhang, L., Shen, Y. and Du, L. “Activation of a cryptic gene cluster in Lysobacter enzymogenes reveals a module/domain portable mechanism of nonribosomal peptide synthetases in the biosynthesis of pyrrolopyrazines.” (2017) Org. Lett. 19: 5010-5013.
4. Spatzal, T., Schlesier, J., Burger, E. M., Sippel, D., Zhang, L., Andrade, S. L. A., Rees, D. C., Einsle, O. “Nitrogenase FeMoco investigated by spatially resolved anomalous dispersion refinement.” (2016) Nat. Commun.. 7: 10902-10532.
5. Anderson, J., Cutsail III, G.E., Rittle, J., Connor, B. A., Gunderson, W. A., Zhang, L.*, Hoffman, B. M.* and Peters, J. C.* “Characterization of an Fe≡N-NH2 intermediate relevant to catalytic N2 reduction to NH3.” (2015) J Am. Chem. Soc. 137: 7803-7809.
(*corresponding authors)
6. Mattle, D., Zhang, L., Gourdon, P., Nissen, P., Rees, D. C. and Meloni, G. “A sulfur-based transport pathway for Cu+-ATPases.” (2015) EMBO J. 16: 728-740.
7. Morrison, C., Hoy, J., Zhang, L., Einsle, O. and Rees, D. C. “Substrate pathways in the nitrogenase MoFe protein by experimental identification of small molecule binding sites.” (2015) Biochemistry 54: 2052-2060.
8. Zhang, L., Morrison, C., Kaiser, J. T. and Rees, D. C. “Nitrogenae MoFe-protein from Clostridium pasteurianum at 1.08 Å Resolution: Comparison to the Azotobacterer vinelandii MoFe-protein.” (2015) Acta Cryst D 71: 274-282.
9. Meloni, G.+*, Zhang, L.+* and Rees, D. C.* “Transmembrane Type-2-like Cu2+ site in the P1B-3-type ATPase CopB: implications for metal selectivity.” (2014) ACS Chem. Biol. 9(1): 116-121.
(+these authors contribute equally, *corresponding authors)
10. Zhang, L., Kaiser, J. T., Meloni, G., Yang, K. Y., Spatzal, T., Andrade, S. L. A., Einsle, O., Howard, J. B. and Rees, D. C. “The sixteenth iron in the nitrogenase MoFe-protein.” (2013) Angew. Chem. Int. Ed. Engl. 52: 10529-10532.
11. Moret, M. E., Zhang, L. and Peters, J. C. “A polar copper-boron one-electron bond.” (2013) J. Am. Chem. Soc. 135: 3792-3795.
12. Pushie, J.M., Zhang, L., Pickering, I. J. and George, G. N. “The fictile coordination chemistry of cuprous-thiolate sites in copper chaperones.” (2012) BBA - Bioenergetics. 1817: 938-947.
13. Spatzal, T., Aksoyoglu, M., Zhang, L. Andrade, S. L.A., Schleicher, E., Weber, S., Rees, D. C. and Einsle, O. “Direct Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor.” (2011) Science. 334:940-940.
14. Ma, Z., Cowart, D. M., Ward, B. P., Arnold, R. J., DiMarchi, R. D., Zhang, L., George, G. N., Scott, R. A. and Giedroc, D. P. “Unnatural amino acid substitution as a Probe of the Allosteric Coupling Pathway in a Mycobacterial Cu(I) Sensor.” (2009) J. Am. Chem. Soc. 131:18044-18045.
15. Zhang, L., Lichtmanneger, J., Summer, K. H., Webb, S., Pickering, I. J. and George, G. N. “Tracing copper-thiomolybdate complexes in a prospective treatment for Wilson’s disease.” (2009) Biochemistry 48:891-897.
16. Bewer, B., Zhang, H., Zhu, Y., Zhang, L., George, G.N., Pickering, I. J. and Chapman, D. “Development of a combined K-edge subtraction and fluorescence subtraction imaging system for small animals.” (2008) Rev. Sci. Instrum. 79:085102-1-085102-3.
17. Zhang, L., Pickering, I. J., Winge, D. R. and George, G. N. “X-ray absorption spectroscopy of cuprous-thiolate clusters in Saccharomyces cerevisiae metallothionein.” (2008) Chem. Biodivers. 5:2042- 2049.
18. Zhang, H., Zhu, Y., Bewer, B., Zhang, L., Korbas, M., Pickering, I. J., George, G. N., Gupta, M. and Chapman, D. “Comparison of iodine K-edge subtraction and fluorescence subtraction imaging in an animal system.” (2008) Nucl. Instrum. Methods Phys. Res. A. 594: 283-291.
19. Chen, X., Hua, H., Balamurugan, K., Kong, X., Zhang, L., George, G. N., Georgiev, O., Schaffner, W. and Giedroc, D. P. “Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.” (2008) Nucleic Acids Res. 36 (9):3128-3138.
20. Zhang, L., Nelson, K. J., Rajagopalan, K.V. and George, G. N. “Structure of molybdenum center in trimethylamine N-oxide reductase from E. Coli.” (2008) Inorg. Chem. 47 (3): 1074-1078.
21. Rigby, K., Zhang, L., Cobine, P. A., Tzagoloff, A., George, G. N. and Winge, D. R. “Characterization of the cytochrome c oxidase assembly factor Cox19 of Saccharomyces cerevisiae.” (2007) J. Biol. Chem. 282 (14): 10233-10244.
22. Coyne, H. J., Ciofi-Baffoni, S., Banci, L., Zhang, L., George, G. N. and Winge, D. R. “The characterization and role of zinc binding in yeast Cox4.” (2007) J. Biol. Chem. 282 (12): 8926- 8934.
23. Liu, T., Ramesh, A., Ward, S. K., Zhang, L., Ma, Z., George, G. N., Talaat, A. M., Sacchettini, J. C. and Giedroc, D. P. “CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator.” (2007) Nature Chem. Biol. 3 (1): 60-68
24. Jiang, D.T., Chen, N., Zhang, L., Malgorzata, K., Wright, G., Igarashi, R., Beauregard, D., Kirkham, M. and McKibben, M. “XAFS at Canadian Light Source.” (2007) AIP Proc. (XAFS13) 882:893-895 (conference paper).
25. Doonan, C. J., Zhang, L., Young, C. G., . “High-resolution X-ray emission spectroscopy of molybdenum compounds.” (2005) Inorg. Chem 44 (8): 2579-2581.